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Positional Nystagmus of Central Origin

Authors: Frederick E, Cobb; Lauren B, Friedman;

Positional Nystagmus of Central Origin

Abstract

Audiometric, electrophysiologic, and radiographic findings for a 68-year-old male with an "imbalance" concern are presented. This paper has a two-fold purpose: (1) to present an unusual electronystagmography case study and (2) to highlight the importance of test conditions in lesion localization. The specific disease pathophysiology remains obscure. Repeated hearing tests documented a known hearing impairment with worsening word-recognition ability of the right ear. An initial electronystagmographic exam was normal except for a mild ageotropic direction-changing positional nystagmus with eyes open and fixed. No repeatable click-evoked auditory brainstem response waveforms could be collected. A magnetic resonance imaging of the brain documents diffuse ischemic white matter disease. A repeated vestibular examination some months later supports the initial findings. The case illustrates the importance of following diagnostic protocol, of repeated measures, and of using both a visual fixation and a nonfixation condition for select electronystagmographic subtests. Se presentan los hallazgos audiométricos, electrofisiológicos y radiográficos de un hombre de 68 años con una "preocupación" en cuánto a su equilibrio. Este artículo tiene un doble propósito: (1) presentar un estudio de caso electronistagmográfico inusual, y (2) destacar la importancia de las condiciones de la prueba en la localización de la lesión. La fisiopatología específica de la enfermedad en este caso sigue siendo obscura. Las pruebas auditivas repetidas documentaron un trastorno ya conocido de la audición, con una capacidad en deterioro del reconocimiento del lenguaje en el oído derecho. El examen electronistagmográfico inicial fue normal excepto por un nistagmo de posición ageotrópico leve de dirección cambiante, con los ojos abiertos y fijos. No se pudieron registrar ondas repetibles de respuesta auditiva del tallo cerebral evocadas por clic. Una resonancia magnética del cerebro documentó una enfermedad isquémica difusa de la sustancia blanca, desde el tallo cerebral a la corteza. Un nuevo examen vestibular, meses después, apoyó los hallazgos iniciales. El caso ilustra la importancia de seguir un protocolo diagnóstico, de las mediciones repetidas, y del uso tanto de condiciones visuales de fijación y de no fijación para seleccionar las sub-pruebas electronistagmográficas.

Related Organizations
Keywords

Male, Dementia, Vascular, Brain, Electronystagmography, Dizziness, Magnetic Resonance Imaging, Nystagmus, Physiologic, Surveys and Questionnaires, Sensation Disorders, Evoked Potentials, Auditory, Brain Stem, Audiometry, Pure-Tone, Humans, Postural Balance, Aged

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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Average
Average
Average
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