
Tribolium castaneum Herbst is a destructive stored product pest. The aggregation pheromone of this pest was prepared via a new and effective strategy. The key steps include the ring-opening reaction of chiral 2-methyloxirane, the stereospecific inversion of chiral secondary tosylate, Li2CuCl4-catalyzed coupling of tosylate with Grignard reagent, and oxidation with RuCl3/NaIO4.
QD241-441, Letter, red flour beetle, Science, Q, chiral 2-methyloxirane, Organic chemistry, total synthesis, aggregation pheromone
QD241-441, Letter, red flour beetle, Science, Q, chiral 2-methyloxirane, Organic chemistry, total synthesis, aggregation pheromone
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