
Historico medico Uma mulher de 58 anos com polineuropatia amiloidotica familiar causada pela mutacao Val30Met (p.Val50Met) no gene da transtirretina (TTR) comecou a apresentar sintomas neuropaticos aos 37 anos e uma biopsia da glândula salivar confirmou a deposicao de amiloide TTR. Foi submetida a transplante hepatico sete anos apos o inicio dos sintomas e fazia uso de imunossupressores, com alteracoes neurologicas estaveis desde entao. Ela tambem apresentava insuficiencia renal cronica (estagio 3b) e um marcapasso implantado devido a doenca do [...]
Heart Failure, Insuficiência Cardíaca, Amyloidosis, Cardiomyopathy, Hypertrophic, Amiloidose, Neuropatias Amiloides Familiares/diagnóstico por imagem, Hipertrofia Ventricular Esquerda, RC666-701, Diseases of the circulatory (Cardiovascular) system, Hypertrophy, Left Ventricular, Carta Científica, Amyloid Neuropathies, Familial/diagnostic imaging, Cardiomiopatia Hipertrófica
Heart Failure, Insuficiência Cardíaca, Amyloidosis, Cardiomyopathy, Hypertrophic, Amiloidose, Neuropatias Amiloides Familiares/diagnóstico por imagem, Hipertrofia Ventricular Esquerda, RC666-701, Diseases of the circulatory (Cardiovascular) system, Hypertrophy, Left Ventricular, Carta Científica, Amyloid Neuropathies, Familial/diagnostic imaging, Cardiomiopatia Hipertrófica
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