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Brazilian Journal of Implantology and Health Sciences
Article . 2024 . Peer-reviewed
License: CC BY
Data sources: Crossref
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ELETROCONVULSOTERAPIA NA DEPRESSÃO ASSOCIADA À DOENÇA DE PARKINSON

Authors: Armando da Silva Moura; Fernanda Maciel Nogueira Martins; Angélica Cintra de Lima; Pedro Henrique Cocco; Caroline Ventura; José Camargo Junior; Maria Eduarda Rosendo de Araujo; +11 Authors

ELETROCONVULSOTERAPIA NA DEPRESSÃO ASSOCIADA À DOENÇA DE PARKINSON

Abstract

A depressão é uma comorbidade frequente na doença de Parkinson (DP), agravando a qualidade de vida dos pacientes devido à interação complexa entre sintomas motores e não motores. A eletroconvulsoterapia (ECT) emergiu como uma opção terapêutica promissora para depressão resistente em DP, com evidências de melhoria significativa dos sintomas depressivos, especialmente em casos onde outras terapias falharam. Este estudo revisa a literatura atual sobre ECT na DP, explorando mecanismos neurobiológicos, protocolos de tratamento e desafios clínicos e éticos. A metodologia incluiu buscas em bases de dados como PubMed, Scopus e Web of Science, com critérios de inclusão para estudos clínicos randomizados, ensaios controlados e revisões sistemáticas. A análise qualitativa dos dados indicou melhorias nos sintomas depressivos e impactos modestos, porém significativos, nos sintomas motores. Os achados ressaltam a necessidade de ensaios clínicos controlados e de longo prazo para validar a segurança e eficácia da ECT, propondo-a como uma abordagem viável para melhorar a saúde mental dos pacientes com DP. Contudo, é crucial avaliar os riscos e benefícios, especialmente quanto aos efeitos cognitivos e motores adversos, e adotar uma abordagem multidisciplinar e individualizada no manejo da depressão em DP.

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold