Artificial Intelligence (AI) is emerging as a transformative force in both drug development and orthodontics. This paper provides an overview of key AI techniques employed in these fields. In drug development, AI is accelerating discovery, development, and delivery through generative models, predictive modeling, image analysis, and natural language processing. Orthodontics benefits from AI through image analysis, treatment planning, and patient experience enhancement. Common AI techniques in both domains include machine learning, deep learning, natural language processing, and computer vision. By leveraging these technologies, researchers and clinicians can achieve significant advancements in drug discovery, treatment efficacy, and patient care.