
Abstract: The topical application of honey on a wound is effective in controlling the wound healing process and results in clean granulation tissues in the wound base. Honey acts as a hyperosmolar medium and prevents microbial growth. Besides that, honey has a high viscosity that forms a physical barrier and cretaes a wet environmet which is very effective in accelerating wound healing. Nutrients in honey increase the supply of local substances that might be useful in reepithelization. In addition, honey contains a catalase enzyme that can influence wound healing.Keywords: honey, wound healingAbstrak: Pemberian madu topikal efektif dalam mengontrol dan menghasilkan dasar luka bergranulasi bersih. Madu bekerja terutama sebagai medium hiperosmolar dan mencegah pertumbuhan bakteri. Madu juga memiliki viskositas tinggi yang membentuk sawar fisik dan menciptakan lingkungan basah; sifat tersebut yang membantu dan mempercepat penyembuhan luka. Kandungan bahan makanan dari madu menambah pasokan bahan lokal yang mungkin membantu mempercepat reepitelisasi. Disamping itu, madu mengandung enzim katalase yang juga mempengaruhi proses penyembuhan luka.Kata kunci: madu, penyembuhan luka
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