Objective: To determine some causes and affecting factors of tubal-peritoneal infertility. To assess the efficacy of laparoscopy in treating tubal-peritoneal infertility. Methods: Prospective study in 126 patients with tubal-peritoneal infertility. Results: Main causes of tubal infertility: Infection: 42.7%, history of operation: 25.6%, endometriosis: 12.8% and other causes and undetermined causes: 18.9%. 79.5% patients have patent tubes through hysterosalpingography. The rate of false obstructed tube through hysterosalpingography was 7.1%. The rate of intrauterine pregnancy after laparoscopy was 21.4%. This rate was associated with the stage of tubal lesons and the highest rate was in the first stage (68.0%). Nobody can get pregnant with the tubal lesions in the third and fourth stage or severe adheson. Conclusion: Main causes of tubal infertility are infection, history of operation and endometriosis. The rate of intrauterine pregnancy and patent tubes in this study is equivalent to some national and international studies. This rate is associated with the stage of tubal le-sions and the degree of tubal adhesion.