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Moxifloxacin-warfarin interaction

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 2012Publisher:Greater Baltimore Medical CenterJournal:Journal of Community Hospital Internal Medicine Perspectives, volume 1, page 11,512 (eissn: 2000-9666,

Authors: Yan Ji; Youssef Hokayem;

doi: 10.3402/jchimp.v1i4.11512

pmid: 23882337

pmc: PMC3714043

Moxifloxacin-warfarin interaction

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Abstract

Two case reports presented here show elevated prothrombin time/international normalized ratios (PT/INR) following coadministration of warfarin and moxifloxacin. Although the underlying mechanism of this interaction still remains unclear, health care providers should be careful when prescribing moxifloxacin to patients on warfarin therapy, especially to patients with low albumin levels. More frequent monitoring of INR in these patients may be warranted.

Related Organizations

MedStar Union Memorial Hospital
United States
Memorial Hospital of South Bend
United States

Keywords

warfarin, Coumadin, Warfarin, Moxifloxacin, Avelox, INR, hypoalbuminemia, anticoagulation, antimicrobial treatment, Case Report, PT/INR, moxifloxacin, Internal medicine, RC31-1245

2 Research products, page 1 of 1

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