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Memory T Cells in Flavivirus Vaccination

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 18 Oct 2018Publisher:MDPI AGJournal:Vaccines, volume 6, page 73 (eissn: 2076-393X,

Authors: Guangyu Li; Cody Teleki; Tian Wang;

doi: 10.3390/vaccines6040073

pmid: 30340377

pmc: PMC6313919

Memory T Cells in Flavivirus Vaccination

- Summary
- Subjects
- Metrics

Abstract

Flaviviruses include many medically important viruses, such as Dengue virus (DENV), Japanese encephalitis (JEV), tick-borne encephalitis (TBEV), West Nile (WNV), yellow fever (YFV), and Zika viruses (ZIKV). Currently, there are licensed human vaccines for DENV, JEV, TBEV and YFV, but not for WNV or ZIKV. Memory T cells play a central role in adaptive immunity and are important for host protection during flavivirus infection. In this review, we discuss recent findings from animal models and clinical trials and provide new insights into the role of memory T cells in host protective immunity upon vaccination with the licensed flavivirus vaccines.

Related Organizations

The University of Texas Medical Branch at Galveston
United States

Keywords

flavivirus, memory T cells, vaccine, R, Medicine, Review

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	15
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%