The Pamir, situated in central Asia, is a result of the ongoing northward advance of the Indian continent, leading to compression of the Asian landmass. While geodetic and seismic data typically indicate that the most significant deformation in Pamir is along its northern boundary, an Mw 7.2 earthquake on 7 December 2015 and an Mw 6.8 earthquake on 23 February 2023 have occurred in the remote interior of Pamir. These two Mw ≥ 6.5 earthquakes, with good observations of satellite synthetic aperture radar data, provide a rare opportunity to gain insights into rupture mechanics and deformation patterns in this challenging-to-reach region. Here, we utilize spaceborne synthetic aperture radar data to determine the seismogenic faults and finite slip models for these two earthquakes. Our results reveal that the 2015 earthquake ruptured a ~88 km long, left-lateral strike-slip fault that dips to northwest. The rupture of the 2015 earthquake extended to the ground surface over a length of ~50 km with a maximum slip of ~3.5 m. In contrast, the 2023 earthquake did not rupture the ground surface, with a maximum slip of ~2.2 m estimated at a depth of ~9 km. Notably, the seismogenic fault of the 2015 earthquake does not align with the primary strand of the Sarez–Karakul fault system (SKFS), and the 2023 earthquake occurred on a previously unmapped fault. The well-determined seismogenic faults for the 2015 and 2023 earthquakes, along with the SKFS and other distributed faults in the region, suggest the existence of a wide shear zone extending from south to north within the central Pamir.