This Special Issue State-of-the-Art on Polymer Science and Technology in Spain is comprised of a collection of 42 publications/contributions related to very different topics undertaken by the numerous research groups working in Spain in Polymer Science and Technology. This monograph collects the contributions of more than 200 different authors from 24 different national Institutions (>30 different centers/departments) from Universities and CSIC centers distributed throughout the whole of Spain. Two-thirds of the contributions to this Special Issue arise from Institutional collaborations, half of which are international collaborations with European research groups and the other half with other international research groups outside Europe including China, Australia or United States of America among others. This brief overview communication provides a general overview of the research lines in Polymer Science and Technology covered in Spain and show most of the representative polymer groups and their distribution throughout Spain. Most of Spanish polymer groups belong to the Grupo Especializado de Polímeros (GEP) being part of the European Polymer Federation (EPF). It also shows how Spanish science about polymers is positioned at European level.