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The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives

Achievements and perspectives
Authors: François Pognan; Thomas Steger-Hartmann; Carlos Díaz; Niklas Blomberg; Frank Bringezu; Katharine Briggs; Giulia Callegaro; +21 Authors

The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives

Abstract

eTRANSAFE is a research project funded within the Innovative Medicines Initiative (IMI), which aims at developing integrated databases and computational tools (the eTRANSAFE ToxHub) that support the translational safety assessment of new drugs by using legacy data provided by the pharmaceutical companies that participate in the project. The project objectives include the development of databases containing preclinical and clinical data, computational systems for translational analysis including tools for data query, analysis and visualization, as well as computational models to explain and predict drug safety events.

Countries
Netherlands, Spain, Netherlands, Italy
Keywords

read across, drug safety, data sharing, :Informàtica::Sistemes d'informació [Àrees temàtiques de la UPC], Drug safety;, Integrative knowledge management, Read across, Toxicology, Article, Pharmacy and materia medica, Data mining; Data sharing; Drug safety; Integrative knowledge management; Predictive modelling; Read across; Toxicology; Translational safety assessment;, Àrees temàtiques de la UPC::Informàtica::Sistemes d'informació, Drug safety, Data mining, integrative knowledge management, translational safety assessment, Toxicology;, Translational safety assessment, R, Predictive modelling, data mining, RS1-441, Medicine, Data sharing, engineering & technology, Mineria de dades, Modeling and simulation in science, predictive modelling, Modeling and simulation in science, engineering & technology, toxicology

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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