
Human endogenous retroviruses (HERV) have been implicated in the pathogenesis of several nervous system disorders including multiple sclerosis and amyotrophic lateral sclerosis. The toxicity of HERV-derived RNAs and proteins for neuronal cells has been demonstrated. The involvement of HERV in the pathogenesis of currently incurable diseases might offer new treatment strategies based on the inhibition of HERV activities by small molecules or therapeutic antibodies.
amyotrophic lateral sclerosis, R, 610, Review, multiple sclerosis, human endogenous retrovirus, RS1-441, Pharmacy and materia medica, Medicine, monoclonal antibodies, info:eu-repo/classification/ddc/610
amyotrophic lateral sclerosis, R, 610, Review, multiple sclerosis, human endogenous retrovirus, RS1-441, Pharmacy and materia medica, Medicine, monoclonal antibodies, info:eu-repo/classification/ddc/610
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 32 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
