
Hyperpolarization is one of the approaches to enhance Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) signal by increasing the population difference between the nuclear spin states. Imaging hyperpolarized solids opens up extensive possibilities, yet is challenging to perform. The highly populated state is normally not replenishable to the initial polarization level by spin-lattice relaxation, which regular MRI sequences rely on. This makes it necessary to carefully “budget” the polarization to optimize the image quality. In this paper, we present a theoretical framework to address such challenge under the assumption of either variable flip angles or a constant flip angle. In addition, we analyze the gradient arrangement to perform fast imaging to overcome intrinsic short decoherence in solids. Hyperpolarized diamonds imaging is demonstrated as a prototypical platform to test the theory.
Magnetic Resonance Spectroscopy, Image Processing, 610, Organic chemistry, Signal-To-Noise Ratio, 530, Phantoms, Article, Imaging, Medicinal and Biomolecular Chemistry, Magnetics, Computer-Assisted, QD241-441, Theoretical and Computational Chemistry, Medicinal and biomolecular chemistry, Image Processing, Computer-Assisted, magnetic resonance imaging, hyperpolarization, Carbon Isotopes, Fourier Analysis, Phantoms, Imaging, Organic Chemistry, Equipment Design, Magnetic Resonance Imaging, 4.1 Discovery and preclinical testing of markers and technologies, flip angle, Chemical Sciences, Calibration, Biomedical Imaging, Diamond, Algorithms
Magnetic Resonance Spectroscopy, Image Processing, 610, Organic chemistry, Signal-To-Noise Ratio, 530, Phantoms, Article, Imaging, Medicinal and Biomolecular Chemistry, Magnetics, Computer-Assisted, QD241-441, Theoretical and Computational Chemistry, Medicinal and biomolecular chemistry, Image Processing, Computer-Assisted, magnetic resonance imaging, hyperpolarization, Carbon Isotopes, Fourier Analysis, Phantoms, Imaging, Organic Chemistry, Equipment Design, Magnetic Resonance Imaging, 4.1 Discovery and preclinical testing of markers and technologies, flip angle, Chemical Sciences, Calibration, Biomedical Imaging, Diamond, Algorithms
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