Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids
Copyright policy )Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids
The antiproliferative activity of a set of seven natural Amaryllidaceae alkaloids and 32 derivatives against four cancer cell lines (A2780, SW1573, T47-D and WiDr) was determined. The best antiproliferative activities were achieved with alkaloids derived from pancracine (2), haemanthamine (6) and haemantidine (7). For each skeleton, some structure-activity relationships were outlined.
antiproliferative activity, Organic chemistry, Antiproliferative activity, Antineoplastic Agents, Phytogenic, Article, Structure-Activity Relationship, QD241-441, Alkaloids, Amarylidaceae alkaloids, Cell Line, Tumor, Liliaceae, Humans, SAR, Cell Proliferation
antiproliferative activity, Organic chemistry, Antiproliferative activity, Antineoplastic Agents, Phytogenic, Article, Structure-Activity Relationship, QD241-441, Alkaloids, Amarylidaceae alkaloids, Cell Line, Tumor, Liliaceae, Humans, SAR, Cell Proliferation
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