Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans
Copyright policy )Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans
A series of polymerizable quaternary ammonium compounds were synthesized with the aim of using them as immobilized antibacterial agents in methacrylate dental composites, and their structures were characterized by FT-IR, 1H-NMR, and 13C-NMR analysis. Their antibacterial activities against the oral bacterium Streptococcus mutans were evaluated in vitro by a Minimum Inhibitory Concentration test, and the results showed that 2-dimethyl-2-hexadecyl-1-methacryloxyethyl ammonium iodide (C16) had the highest antibacterial activity against S. mutans, and 2-dimethyl-2-pentyl-1-methacryloxyethyl ammonium iodide (C5) and 2-dimethyl-2-octyl-1-methacryloxyethyl ammonium iodide (C8) did not show any inhibition.
- North China University of Technology China (People's Republic of)
- University of Turku Finland
- South China University of Technology China (People's Republic of)
- National Institute for Health and Welfare Finland
- TURUN YLIOPISTO Finland
ta313, methacrylate, Organic chemistry, Microbial Sensitivity Tests, Article, Anti-Bacterial Agents, Quaternary Ammonium Compounds, Streptococcus mutans, antibacterial, Dental Materials, QD241-441, dental materials, Humans, Methacrylates, quaternary ammonium compounds, ta999
ta313, methacrylate, Organic chemistry, Microbial Sensitivity Tests, Article, Anti-Bacterial Agents, Quaternary Ammonium Compounds, Streptococcus mutans, antibacterial, Dental Materials, QD241-441, dental materials, Humans, Methacrylates, quaternary ammonium compounds, ta999
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