
New coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5-(phenylamino)-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (8) and 7-[(5-mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)methoxy]-2H-chromen-2-one (9) were prepared starting from the natural compound umbelliferone (1). The newly synthesized compounds were characterized by elemental analysis and spectral studies (IR, 1H-NMR and 13C-NMR).
Models, Molecular, Biological Products, Magnetic Resonance Spectroscopy, Chemistry, Pharmaceutical, phosphorous oxychloride, Organic chemistry, Acetates, thiosemicarbazide, coumarin, ethyl bromoacetate, Article, Hydrocarbons, Brominated, Semicarbazides, umbelliferone, QD241-441, Thiadiazoles, Thermodynamics, Umbelliferones, 1,3,4-thiadiazole
Models, Molecular, Biological Products, Magnetic Resonance Spectroscopy, Chemistry, Pharmaceutical, phosphorous oxychloride, Organic chemistry, Acetates, thiosemicarbazide, coumarin, ethyl bromoacetate, Article, Hydrocarbons, Brominated, Semicarbazides, umbelliferone, QD241-441, Thiadiazoles, Thermodynamics, Umbelliferones, 1,3,4-thiadiazole
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