
In the continued search for novel bioactive substances from the Taiwanese octocoral Briareum excavatum collected at Orchid Island, three new briarane-type diterpenoids, briacavatolides D–F (1–3) were isolated from the acetone extract. The structures of these compounds were elucidated by extensive NMR spectroscopic analysis and physical data. The anti-HCMV (human cytomegalovirus) activity of 1–3 and their cytotoxicity against selected cancer cell lines were evaluated.
Aquatic Organisms, Biological Products, Magnetic Resonance Spectroscopy, Taiwan, Cytomegalovirus, Anthozoa, Antiviral Agents, Article, Mice, Cell Line, Tumor, Animals, Humans, <em>Briareum excavatum</em>; briarane-type diterpenoid; cytotoxicity; anti-HCMV, Diterpenes, HT29 Cells
Aquatic Organisms, Biological Products, Magnetic Resonance Spectroscopy, Taiwan, Cytomegalovirus, Anthozoa, Antiviral Agents, Article, Mice, Cell Line, Tumor, Animals, Humans, <em>Briareum excavatum</em>; briarane-type diterpenoid; cytotoxicity; anti-HCMV, Diterpenes, HT29 Cells
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