
Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M–O (1–3). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.
Magnetic Resonance Spectroscopy, Pancreatic Elastase, Neutrophils, Anti-Inflammatory Agents, <em>Junceella juncea</em>, briaranes, Anthozoa, Article, Superoxides, Animals, Humans, Diterpenes, anti-inflammatory activity
Magnetic Resonance Spectroscopy, Pancreatic Elastase, Neutrophils, Anti-Inflammatory Agents, <em>Junceella juncea</em>, briaranes, Anthozoa, Article, Superoxides, Animals, Humans, Diterpenes, anti-inflammatory activity
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