Parameter estimation is one of the most important tasks in statistics, and is key to helping people understand the distribution behind a sample of observations. Traditionally, parameter estimation is done either by closed-form solutions (e.g., maximum likelihood estimation for Gaussian distribution) or by iterative numerical methods such as the Newton–Raphson method when a closed-form solution does not exist (e.g., for Beta distribution). In this paper, we propose a transformer-based approach to parameter estimation. Compared with existing solutions, our approach does not require a closed-form solution or any mathematical derivations. It does not even require knowing the probability density function, which is needed by numerical methods. After the transformer model is trained, only a single inference is needed to estimate the parameters of the underlying distribution based on a sample of observations. In the empirical study, we compared our approach with maximum likelihood estimation on commonly used distributions such as normal distribution, exponential distribution and beta distribution. It is shown that our approach achieves similar or better accuracy as measured by mean-square-errors.