<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Angioedema and Fatty Acids

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 20 Aug 2021 English Publisher:MDPI AGJournal:International Journal of Molecular Sciences, volume 22, page 9,000 (eissn: 1422-0067,

Authors: Motonobu Nakamura; Yu Sawada; Hitomi Sugino; Akane Wada;

doi: 10.3390/ijms22169000

pmid: 34445711

pmc: PMC8396478

Angioedema and Fatty Acids

- Summary
- Subjects
- Related research
  (3)
- Metrics

Abstract

Angioedema is a life-threatening emergency event that is associated with bradykinin and histamine-mediated cascades. Although bradykinin-mediated angioedema currently has specific therapeutic options, angioedema is sometimes intractable with current treatments, especially histamine-mediated angioedema, suggesting that some other mediators might contribute to the development of angioedema. Fatty acids are an essential fuel and cell component, and act as a mediator in physiological and pathological human diseases. Recent updates of studies revealed that these fatty acids are involved in vascular permeability and vasodilation, in addition to bradykinin and histamine-mediated reactions. This review summarizes each fatty acid’s function and the specific receptor signaling responses in blood vessels, and focuses on the possible pathogenetic role of fatty acids in angioedema.

Related Organizations

University of Occupational and Environmental Health Japan
Japan

Keywords

Capillary Permeability, Fatty Acids, Prostaglandins, Humans, Review, Angioedema, Bradykinin, Histamine

3 Research products, page of 1

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	5
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average