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RNAs in Brain and Heart Diseases

Name: RNAs in Brain and Heart Diseases
Keywords: Brain Diseases, blood [Biomarkers], RNA, Untranslated, blood [Brain Diseases], metabolism [Heart Diseases], Heart Diseases, blood [RNA, Untranslated], metabolism [Cell-Free Nucleic Acids], metabolism [Brain Diseases], blood [Heart Diseases]

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 25 May 2020 Germany English Publisher:MDPI AGJournal:International Journal of Molecular Sciences, volume 21, page 3,717 (eissn: 1422-0067,

Authors: Beis, Dimitris; Zerr, Inga; Martelli, Fabio; Doehner, Wolfram; Devaux, Yvan; Beis, Dimitris; Zebrafish Disease Models lab, Center for Experimental Surgery Clinical and Translational Research, Biomedical Research Foundation Academy of Athens, 11527 Athens, Greece, dbeis@bioacademy.gr; Zerr, Inga; Department of Neurology, Clinical Dementia Centre and DZNE, University Medical School, Georg-August University, 37075 Göttingen, Germany, ingazerr@med.uni-goettingen.de; +3 Authors

doi: 10.3390/ijms21103717

pmid: 32466222

pmc: PMC7279324

RNAs in Brain and Heart Diseases

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Abstract

In the era of single-cell analysis, one always has to keep in mind the systemic nature of various diseases and how these diseases could be optimally studied. Comorbidities of the heart in neurological diseases as well as of the brain in cardiovascular diseases are prevalent, but how interactions in the brain–heart axis affect disease development and progression has been poorly addressed. Several brain and heart diseases share common risk factors. A better understanding of the brain–heart interactions will provide better insights for future treatment and personalization of healthcare, for heart failure patients’ benefit notably. We review here emerging evidence that studying noncoding RNAs in the brain–heart axis could be pivotal in understanding these interactions. We also introduce the Special Issue of the International Journal of Molecular Sciences RNAs in Brain and Heart Diseases—EU-CardioRNA COST Action.

Country

Germany

Related Organizations

Helmholtz Association of German Research Centres
Germany
Charité - University Medicine Berlin
Germany
University Medical School
Hungary
Cardiology Department
Switzerland
Berlin Institute of Health at Charité
Germany

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Keywords

Brain Diseases, blood [Biomarkers], RNA, Untranslated, blood [Brain Diseases], metabolism [Heart Diseases], Heart Diseases, blood [RNA, Untranslated], metabolism [Cell-Free Nucleic Acids], metabolism [Brain Diseases], blood [Heart Diseases], metabolism [RNA, Untranslated], Editorial, Animals, Humans, blood [Cell-Free Nucleic Acids], Cell-Free Nucleic Acids, Biomarkers, Signal Transduction, ddc: ddc:540

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	7
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%