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The Hippo Pathway in Kidney Development

Authors: Caroline M. Lara; Toni Castro Torres; Usaid Mazhar; Dorrian G. Cohen; Rebecca A. Wingert;

The Hippo Pathway in Kidney Development

Abstract

The kidney, a complex organ crucial for a multitude of homeostatic functions, including the maintenance of fluid and electrolyte balance, removal of various metabolic waste products, and hormone production, undergoes intricate developmental processes to form functional nephron units. Understanding the mechanisms behind kidney development is paramount for elucidating the etiology of renal congenital disabilities and acquired diseases. The Hippo pathway is known for its involvement in various cellular functions, including cell fate determination and differentiation, and is a critical player in renal organogenesis. Here, we discuss research findings about the roles that Hippo signaling plays in kidney formation.

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Keywords

TAZ, Hippo pathway, Science, Q, YAP, nephron, Article, kidney development

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
Green
gold