The operation of unmanned aircraft systems in shared airspace can serve as an accelerator for the global economy and a sensitive addition to the existing mix of transportation modes. For these reasons, concepts of Unmanned Traffic Management have been recently published, defining advanced rules for all potential participants in the operation of unmanned systems. Airspace primarily dedicated to automated unmanned system operations, referred to as U-space in Europe, needs to be designated with consideration for the surrounding airspace. This is especially important in cases where the airspace is controlled, and when declaring U-space airspace, it is necessary to pay particular attention to the density of surrounding air traffic. The goal of this article is to assess the suitability of establishing U-space airspace for Urban Air Mobility in terms of traffic density in a controlled area above the selected metropolis, which is Prague, Czech Republic. To achieve this goal, data on air traffic in the given area were analyzed to obtain precise information about the traffic distribution. Areas in which the establishment of U-space airspace is possible both without implementing dynamic reconfiguration and with the application of the dynamic reconfiguration concept were also selected. The result is the determination of whether it is possible to establish U-space in airspace, as in the analyzed case of the Ruzyně CTR, U-space can be introduced in 83 % of the territory.