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Diagnostics
Article . 2022 . Peer-reviewed
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Diagnostics
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CD8 Encephalitis: A Diagnostic Dilemma

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 04 Nov 2022 English Publisher:MDPI AGJournal:Diagnostics, volume 12, page 2,687 (eissn: 2075-4418, Copyright policy )
Authors: Rohan Sharma; Thomas Spradley; Morgan Campbell; Shubham Biyani; Pulkit Singhal; Hisham Elkhider; Krishna Nalleballe; +3 Authors

doi: 10.3390/diagnostics12112687

pmid: 36359530

pmc: PMC9689240

CD8 Encephalitis: A Diagnostic Dilemma

Abstract

CD8+ encephalitis is a subacute encephalopathy associated with HIV infection. Pathophysiology is thought to be auto-reactive CD8+ cells attacking on HIV infected CD4+ cells and ‘viral escape’ phenomena (replication of CD8+ cells in CSF). We present a case of a 45-year-old man with well controlled HIV who developed CD8 encephalitis following Herpes simplex encephalitis. He had persistent encephalopathy for several weeks with status epilepticus and agitated delirium, and diagnosis remained elusive until a brain biopsy confirmed the diagnosis.

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Keywords

Medicine (General), CD8 encephalitis, R5-920, encephalitis, HSV, HIV, Case Report

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    influence
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Average
Average
Green
gold
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