The current Special Issue is addressed to architects and engineers. Design and research are areas connecting their activities. A review of 17 published articles confirms the fact that the interface between architecture and engineering is multidimensional. The ways of finding points of contact between the two industries are highlighted. This is favoured by the dynamically changing reality, supported by new design paradigms and new research techniques. The multi-threaded subject matter of the articles is reduced to six blocks: research scopes, methods, design aspects, context, nature of research, and economy and cost calculation. Each of the articles in these six blocks has its weight, and so, in the “Nature of research” block, the following areas have been underscored: laboratory tests, in situ research, field investigations, and street perception experiments. The “Design aspects” block includes design-oriented thinking, geometrical forms, location of buildings, cost prediction, attractor and distractor elements, and shaping spatial structures. The new design and research tools are an inspiration and a keystone bonding architects and engineers.