This study employs RGB imagery and machine learning techniques to detect Tagosodes orizicolus infestations in “Tinajones” rice crops during the flowering stage, a critical challenge for agriculture in northern Peru. High-resolution images were acquired using an unmanned aerial vehicle (UAV) and preprocessed by extracting 256 × 256-pixel segments, focusing on three classes: infested zones, non-cultivated areas, and healthy rice crops. A dataset of 1500 images was constructed and utilized to train deep learning models based on VGG16 and ResNet50. Both models exhibited highly comparable performance, with VGG16 attaining a precision of 98.274% and ResNet50 achieving a precision of 98.245%, demonstrating their effectiveness in identifying infestation patterns with high reliability. To automate the analysis of complete UAV-acquired images, a web-based application was developed. This system receives an image, segments it into grids, and preprocesses each section using resizing, normalization, and dimensional adjustments. The pretrained VGG16 model subsequently classifies each segment into one of three categories: infested zone, non-cultivated area, or healthy crop, overlaying the classification results onto the original image to generate an annotated visualization of detected areas. This research contributes to precision agriculture by providing an efficient and scalable computational tool for early infestation detection, thereby supporting timely intervention strategies to mitigate potential crop losses.