Macropinocytosis Exploitation by Cancers and Cancer Therapeutics
Copyright policy )Macropinocytosis Exploitation by Cancers and Cancer Therapeutics
Macropinocytosis has long been known as a primary method for cellular intake of fluid-phase and membrane-bound bulk cargo. This review seeks to re-examine the latest studies to emphasize how cancers exploit macropinocytosis to further their tumorigenesis, including details in how macropinocytosis can be adapted to serve diverse functions. Furthermore, this review will also cover the latest endeavors in targeting macropinocytosis as an avenue for novel therapeutics.
- University of California, San Francisco United States
- UCSF Helen Diller Family Comprehensive Cancer Center United States
receptor-dependent macropinocytosis, proteoglycan, macropinocytosis, Physiology, altered membrane dynamics, pathogen entry, targeted cancer therapy, tumor selective internalization, neurodegenerative disease, macropinosome, G-protein Coupled Receptor, receptor tyrosine kinase, QP1-981
receptor-dependent macropinocytosis, proteoglycan, macropinocytosis, Physiology, altered membrane dynamics, pathogen entry, targeted cancer therapy, tumor selective internalization, neurodegenerative disease, macropinosome, G-protein Coupled Receptor, receptor tyrosine kinase, QP1-981
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).80 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!