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Frontiers in Physics
Article . 2019 . Peer-reviewed
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Frontiers in Physics
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Frontiers in Physics
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Automation of Bone Tissue Histology

Authors: Yaikova V.; Gerasimov O.; Fedyanin A.; Zaytsev M.; Baltin M.; Baltina T.; Sachenkov O.;

Automation of Bone Tissue Histology

Abstract

In abstract methods of automation of histology, bone structure is considered. Possible inputs are snapshots from a microscope or computed tomography slices. An algorithm is proposed that differentiates objects according to their color (or grayscale) and recover morphology topology. An algorithm to separate morphological objects by their dimensions and color parameters was built. Measured parameters were bone surface, bone area, porosity, cortical thickness, canal number, canal area, and etc. Additionally, we measured the anisotropy properties of the bone tissue: distribution of porosity direction and degree of porosity elongation. A bone example was scanned by computed tomography. All data were measured by the proposed method and the results presented. An example algorithm of work on computed tomography data is shown in this work.

Country
Russian Federation
Related Organizations
Keywords

microtomography, Microscopy, quantitative phase imaging, Physics, QC1-999, 600, Holographic microscopy, label-free, 620, holographic microscopy, Interferometric microscopy, Microtomography, Quantitative phase imaging, microscopy, interferometric microscopy, Label-free

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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
10
Top 10%
Top 10%
Top 10%
gold