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P311, Friend, or Foe of Tissue Fibrosis?

descriptionPublicationkeyboard_double_arrow_right Article 12 Oct 2018 Belgium Publisher:Frontiers Media SAJournal:Frontiers in Pharmacology, volume 9 (eissn: 1663-9812, Copyright policy )
Authors: Stradiot, Leslie; Mannaerts, Inge; van Grunsven, Leo A.;

doi: 10.3389/fphar.2018.01151

pmid: 30369881

pmc: PMC6194156

P311, Friend, or Foe of Tissue Fibrosis?

Abstract

P311 was first identified by the group of Studler et al. (1993) in the developing brain. In healthy, but mainly in pathological tissues, P311 is implicated in cell migration and proliferation. Furthermore, evidence in models of tissue fibrosis points to the colocalization with and the stimulation of transforming growth factor β1 by P311. This review provides a comprehensive overview on P311 and discusses its potential as an anti-fibrotic target.

Country
Belgium
Related Organizations
Keywords

Pharmacology, proliferation, fibrosis, TGFβ1, Therapeutics. Pharmacology, RM1-950, P311, migration, Migration

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 13
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
13
Top 10%
Average
Top 10%
Green
gold
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