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Frontiers in Behavioral Neuroscience
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The Neurobiology of Cannabis Use Disorders: A Call for Evidence

A call for evidence
Authors: Lorenzetti, V; Cousijn, J; Solowij, N; Garavan, H; Suo, C; Yücel, M; Verdejo-García, A;

The Neurobiology of Cannabis Use Disorders: A Call for Evidence

Abstract

Using cannabis is perceived by many as relatively harmless, but the adverse effects of problematic cannabis use are significant. Thirteen million individuals globally have Cannabis Use Disorders (CUDs; UNODC, 2015), with relapse rates comparable to those of other substance use disorders (~52–70%; Budney et al., 1999; Chauchard et al., 2013). Contrasting non-problematic recreational cannabis use, severe forms of CUD involve compulsive use despite significant harms to mental health; high stress levels (craving, withdrawal); cognitive deficits; academic and work absenteeism; and significant risky behaviors, such as driving and operating machinery while intoxicated. Worryingly, the concentration of Δ9-tetrahydrocannabinol, the compound driving the addiction liability of cannabis, has risen in cannabis products over the past decade (UNODC, 2015).

Countries
Australia, Netherlands, Australia, Australia
Keywords

cannabis, evidence, neurobiology, call, Addiction, Neurosciences. Biological psychiatry. Neuropsychiatry, dependence, Social and Behavioral Sciences, Education, Neurobiology, Stress, Physiological, disorders, Cannabis use Disorder, RC321-571, Neuroscience

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    19
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
19
Top 10%
Average
Top 10%
Green
gold