Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Frontiers in Microbi...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
Frontiers in Microbiology
Article . 2016 . Peer-reviewed
Data sources: Crossref
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
Frontiers in Microbiology
Article
License: CC BY
Data sources: UnpayWall
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
PubMed Central
Other literature type . 2016
License: CC BY
Data sources: PubMed Central
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
Frontiers in Microbiology
Article . 2016 . Peer-reviewed
Data sources: Frontiers
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
https://dx.doi.org/10.60692/qh...
Other literature type . 2016
Data sources: Datacite
https://dx.doi.org/10.60692/9r...
Other literature type . 2016
Data sources: Datacite
versions View all 6 versions
addClaim

This Research product is the result of merged Research products in OpenAIRE.

You have already added 0 works in your ORCID record related to the merged Research product.

A Novel H1N2 Influenza Virus Related to the Classical and Human Influenza Viruses from Pigs in Southern China

فيروس إنفلونزا H1N2 جديد يتعلق بفيروسات الإنفلونزا الكلاسيكية والبشرية من الخنازير في جنوب الصين
Authors: Yafen Song; Xiaowei Wu; Nianchen Wang; Guowen Ouyang; Nannan Qu; Jin Cui; Qingyun Yan; +2 Authors

A Novel H1N2 Influenza Virus Related to the Classical and Human Influenza Viruses from Pigs in Southern China

Abstract

Le sud de la Chine a longtemps été considéré comme un épicentre des virus grippaux pandémiques. L'environnement spécial, le mode de reproduction et le mode de vie dans le sud de la Chine offrent plus de chances aux oiseaux aquatiques sauvages, à la volaille domestique, aux porcs et aux humains d'être en contact. Cela crée la possibilité de transmission interspécifique et de génération de nouveaux virus grippaux. Dans cette étude, nous avons signalé un nouveau virus grippal H1N2 réassorti provenant de porcs du sud de la Chine. Selon les arbres phylogénétiques et l'homologie de la séquence nucléotidique, le virus a été confirmé comme étant un nouveau virus H1N2 triple réassortant contenant des gènes de porcs classiques (gènes PB2, PB1, HA, NP et NS), de porcs triple réassortants (gènes PA et M) et de lignées humaines récentes (gène NA). Il a indiqué que le nouveau virus de réassortiment parmi les virus de la grippe humaine et porcine s'est produit chez les porcs dans le sud de la Chine. L'isolement des nouveaux virus de la grippe H1N2 réassortis fournit une preuve supplémentaire que les porcs sont des « navires de mélange », et la surveillance du virus de la grippe porcine dans le sud de la Chine fournira des informations importantes sur l'évaluation génétique et la variation antigénique du virus de la grippe porcine pour formuler les mesures de prévention et de contrôle des virus.

El sur de China ha sido considerado durante mucho tiempo como un epicentro de los virus de la gripe pandémica. El entorno especial, el modo de reproducción y el estilo de vida en el sur de China brindan más oportunidades para que las aves acuáticas silvestres, las aves de corral domésticas, los cerdos y los humanos estén en contacto. Esto crea la oportunidad para la transmisión entre especies y la generación de nuevos virus de influenza. En este estudio, informamos sobre un nuevo virus de influenza H1N2 reagrupado de cerdos en el sur de China. De acuerdo con los árboles filogenéticos y la homología de la secuencia de nucleótidos, se confirmó que el virus era un nuevo virus H1N2 de triple reagrupación que contenía genes de linajes porcinos clásicos (genes PB2, PB1, HA, NP y NS), porcinos de triple reagrupación (genes PA y M) y humanos recientes (gen NA). Indicó que el nuevo virus de redistribución entre los virus de la influenza humana y porcina ocurrió en cerdos en el sur de China. El aislamiento de los nuevos virus de la influenza H1N2 reagrupados proporciona evidencia adicional de que los cerdos son "recipientes de mezcla", y la vigilancia del virus de la influenza porcina en el sur de China proporcionará información importante sobre la evaluación genética y la variación antigénica del virus de la influenza porcina para formular las medidas de prevención y control de los virus.

Southern China has long been considered to be an epicenter of pandemic influenza viruses. The special environment, breeding mode, and lifestyle in southern China provides more chances for wild aquatic birds, domestic poultry, pigs, and humans to be in contact. This creates the opportunity for interspecies transmission and generation of new influenza viruses. In this study, we reported a novel reassortant H1N2 influenza virus from pigs in southern China. According to the phylogenetic trees and homology of the nucleotide sequence, the virus was confirmed to be a novel triple-reassortant H1N2 virus containing genes from classical swine (PB2, PB1, HA, NP, and NS genes), triple-reassortant swine (PA and M genes), and recent human (NA gene) lineages. It indicated that the novel reassortment virus among human and swine influenza viruses occurred in pigs in southern China. The isolation of the novel reassortant H1N2 influenza viruses provides further evidence that pigs are "mixing vessels," and swine influenza virus surveillance in southern China will provide important information about genetic evaluation and antigenic variation of swine influenza virus to formulate the prevention and control measures for the viruses.

لطالما اعتُبر جنوب الصين مركزًا لفيروسات الأنفلونزا الوبائية. توفر البيئة الخاصة وطريقة التكاثر ونمط الحياة في جنوب الصين المزيد من الفرص للطيور المائية البرية والدواجن المنزلية والخنازير والبشر للاتصال. وهذا يخلق فرصة لانتقال بين الأنواع وتوليد فيروسات إنفلونزا جديدة. في هذه الدراسة، أبلغنا عن فيروس إنفلونزا H1N2 جديد من الخنازير في جنوب الصين. وفقًا للأشجار الوراثية وتماثل تسلسل النيوكليوتيدات، تم تأكيد أن الفيروس هو فيروس H1N2 ثلاثي التوافقي يحتوي على جينات من الخنازير الكلاسيكية (PB2، PB1، HA، NP، و NS الجينات)، والخنازير ثلاثية التوافقي (PA و M الجينات)، والأنساب البشرية الحديثة (NA الجينات). وأشارت إلى أن فيروس إعادة التشكيل الجديد بين فيروسات إنفلونزا البشر والخنازير حدث في الخنازير في جنوب الصين. يوفر عزل فيروسات إنفلونزا H1N2 الجديدة دليلًا إضافيًا على أن الخنازير "تختلط بالأوعية"، وستوفر مراقبة فيروس إنفلونزا الخنازير في جنوب الصين معلومات مهمة حول التقييم الجيني والاختلاف المستضدي لفيروس إنفلونزا الخنازير لصياغة تدابير الوقاية والسيطرة على الفيروسات.

Related Organizations
Keywords

China, Epidemiology, Influenza A virus subtype H5N1, Infectious disease (medical specialty), Microbiology, Social Distancing, H5N1 genetic structure, molecular characterization, swine influenza virus, Virology, Health Sciences, Epidemiology and Pathogenesis of Respiratory Viral Infections, FOS: Mathematics, Pathology, Disease, Biology, Geography, H1N2, phylogenetic analysis, Modeling the Dynamics of COVID-19 Pandemic, Virus, Southern china, Coronavirus disease 2019 (COVID-19), Archaeology, reassortant, Influenza A virus, Modeling and Simulation, Physical Sciences, Human influenza, Medicine, Influenza Virus Research and Epidemiology, Mathematics

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    5
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
Green
gold