Bronchiectasis is an uncommon chronic obstructive lung disease caused by chronic airway inflammation leading to irreversible bronchial dilation and destruction of medium-sized airways. In this case, we treated a bronchiectasis patient with a combination of osteopathic manipulative treatment (OMT) techniques including myofascial release and lymphatic techniques as adjunctive treatments in addition to other pharmacologic and nonpharmacologic therapies; OMT was shown to improve subjective symptoms of airway congestion as well as reduce frequency of emergency room visits and hospital admissions for this patient.