This is a clinical case describing a hypertensive female patient with a drug-influenced gingival enlargement (DIGE) on the labial and lingual gingivae of the lower anterior dentition. DIGE is attributed to the prolonged use of medications in a susceptible individual. She had undergone non-surgical periodontal therapy prior to surgical intervention for the removal of gingival enlargement (GE) using diode laser therapy. A diode laser is a type of laser widely used in dentistry. This laser therapy is a less invasive technique for the removal of GE. After 6 months of follow-up, no recurrence of GE was observed, and regular supportive periodontal therapy was adopted to sustain the gingival health. The utilization of the diode laser showed excellent predictability and clinical outcomes.