_Streptococcus pyogenes_, commonly known as group A _Streptococcus_ (GAS), is a bacterium that causes a wide range of clinical diseases. Its ability to cause superficial, invasive, and even life-threatening infections makes it an important pathogen that requires prompt diagnosis and treatment. It is a Gram-positive bacterium. These infections involve the bloodstream and can lead to sepsis, toxic shock syndrome, pneumonia, and necrotizing fasciitis. These infections require immediate medical attention and treatment with high doses of antibiotics and aggressive supportive care. _S. pyogenes_ is a bacterium that causes a wide range of clinical diseases. Its ability to cause superficial, invasive, and even life-threatening infections makes it an important pathogen that requires prompt diagnosis and treatment. With the appropriate use of antibiotics and appropriate infection control measures, the incidence of _S. pyogenes_ infections can be significantly reduced. The main objectives of this review are to know the causes of _Streptococcus pyogenes_.