This work provides a historical overview of how heredity has been understood and a key problem in quantum biology is shed light on: the role of quantum mechanics in point mutation, a cornerstone of evolution. A foundation in core genetic concepts is provided, including the meaning and location of chromosomes and genes in cells, DNA structure, the replication mechanism, the genetic code, and tautomeric forms, mutation types, natural selection, neo-Darwinism. Finally, how Heisenberg uncertainty and quantum tunneling facilitate mutation is explored.