
We think that this review (1) is in actual fact very relevant, but somewhat incomplete as it does not include repetitive transcranial magnetic stimulation (rTMS) as a treatment option. This method, though not approved in Germany, has been cleared for use in the United States and several European and non-European countries. In Germany, rTMS may be used within the legal framework of an individual treatment attempt (compassionate use). Scientific evidence of its efficacy in chronic and treatment-resistant depression is available, showing both statistically significant and clinically relevant benefits (2) and recently it has been recommended in the guidelines on the therapeutic use of repetitive transcranial magnetic stimulation with a high (A) level of evidence (3).
Electroshock, Cognitive Behavioral Therapy, Depression, Critical Pathways, Humans, Antidepressive Agents
Electroshock, Cognitive Behavioral Therapy, Depression, Critical Pathways, Humans, Antidepressive Agents
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