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Hemocompatibility of Diamond-Like Carbon Coating

Authors: I, Dion; X, Roques; C, Baquey; E, Baudet; B, Basse Cathalinat; N, More;

Hemocompatibility of Diamond-Like Carbon Coating

Abstract

The new prosthetic heart valve that has been designed by FII Company and Pr. Baudet involves a new “composite” material: titanium alloy T16A14V coated with Diamond-like Carbon. The purpose of this study was to evaluate the in vitro hemocompatibility of this new material in terms of protein adsorption and platelet retention. The static protein adsorption test gave interesting results, particularly for the albumin assay (237%) compared to the results obtained with a silicone elastomer chosen as a reference; the fibrinogen quantity, adsorbed on the surface of the material was slightly higher than that adsorbed on the silicone surface. Platelets adhere quite twice as much as they do on the reference surface. Such investigations showed good hemocompatibility results and should initiate further studies.

Keywords

Titanium, Proteins, Biocompatible Materials, Carbon, Platelet Adhesiveness, Heart Valve Prosthesis, Materials Testing, Alloys, Silicone Elastomers, Humans, Adsorption, Radionuclide Imaging

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    influence
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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
48
Top 10%
Top 10%
Average
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