This paper focuses on the real time detection of sand production of oil and gas wells. According to the movement rule of the sand in the flow, Sand in the pipeline making the collision with the pipe at the elbow, producing a sound signal, which is regarded as sand production signal. This paper analyzes the characteristic of the sand production signal, establish the theoretical models and calculation method between the sand production signal and sand production rate. Through the laboratory simulation experiments combined with the testing system, test results show the rationality and practical of the sand production model.