Effect of atorvastatin on joint contracture development in a rat model of posttraumatic joint contracture of the knee

descriptionPublicationkeyboard_double_arrow_right Conference object 06 Nov 2018 English Publisher:German Medical Science GMS Publishing House; Düsseldorf

Authors: Baranowski, A; Slotina, E; Mickan, T; Ritz, U; Schmidtmann, I; Ackermann, A; Rommens, PM;

doi: 10.3205/18dkou705

Effect of atorvastatin on joint contracture development in a rat model of posttraumatic joint contracture of the knee

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Abstract

Objectives: Myofibroblasts have been associated with increased posttraumatic joint contracture, which has a devastating impact on articular function and activities of daily life. Atorvastatin has shown to reduce the rate of activation and proliferation of cardiac, hepatic and pulmonary myofibroblasts.[for full text, please go to the a.m. URL]

Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2018)

Related Organizations

Johannes Gutenberg University of Mainz
Germany

Keywords

trauma, ddc: 610, joint contracture, rat model, myofibroblasts, atorvastatin, 610 Medical sciences; Medicine

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