
pmid: 18217566
pmc: PMC3375809
Résumé Nous décrivons un cas pédiatrique mortel de fièvre pourprée des montagnes Rocheuses au Panama, le premier, à notre connaissance, depuis les années 1950. Le diagnostic a été établi par immunohistochimie, PCR et isolement de Rickettsia rickettsii à partir de tissus post-mortem. Le typage moléculaire a démontré une forte parenté de l'isolat avec des souches de R. rickettsii d'Amérique centrale et du Sud.
Resumen Describimos un caso pediátrico fatal de fiebre manchada de las Montañas Rocosas en Panamá, el primero, hasta donde sabemos, desde la década de 1950. El diagnóstico se estableció mediante inmunohistoquímica, PCR y aislamiento de Rickettsia rickettsii de tejidos post mortem. La tipificación molecular demostró una fuerte relación del aislado con cepas de R. rickettsii de América Central y del Sur.
Abstract We describe a fatal pediatric case of Rocky Mountain spotted fever in Panama, the first, to our knowledge, since the 1950s. Diagnosis was established by immunohistochemistry, PCR, and isolation of Rickettsia rickettsii from postmortem tissues. Molecular typing demonstrated strong relatedness of the isolate to strains of R. rickettsii from Central and South America.
وصفنا حالة مميتة للأطفال من حمى روكي ماونتن المرقطة في بنما، وهي الأولى، على حد علمنا، منذ الخمسينيات. تم إنشاء التشخيص عن طريق الكيمياء النسيجية المناعية، PCR، وعزل Rickettsia rickettsii من أنسجة ما بعد الوفاة. أظهرت الكتابة الجزيئية ارتباطًا قويًا للعزل بسلالات R. rickettsii من أمريكا الوسطى والجنوبية.
Rift Valley Fever, Panama, Molecular Sequence Data, Rickettsia rickettsii, Infectious and parasitic diseases, RC109-216, FOS: Health sciences, Polymerase Chain Reaction, Microbiology, Agricultural and Biological Sciences, Fatal Outcome, Virology, Health Sciences, Animals, Humans, Rickettsia, Rocky Mountain Spotted Fever, Biology, Ecology, Evolution, Behavior and Systematics, Immunology and Microbiology, Base Sequence, Ecology, molecular typing, R, Dispatch, Life Sciences, Typing, Immunohistochemistry, Bluetongue Virus and Culicoides-Borne Diseases in Europe, RMSF, Virus, PCR, Infectious Diseases, Tick-Borne Diseases and Pathogens Transmission, Child, Preschool, FOS: Biological sciences, immunohistochemistry, Medicine, Female, Parasitology, Rocky Mountain spotted fever, Viral Hemorrhagic Fevers and Zoonotic Infections, Spotted fever
Rift Valley Fever, Panama, Molecular Sequence Data, Rickettsia rickettsii, Infectious and parasitic diseases, RC109-216, FOS: Health sciences, Polymerase Chain Reaction, Microbiology, Agricultural and Biological Sciences, Fatal Outcome, Virology, Health Sciences, Animals, Humans, Rickettsia, Rocky Mountain Spotted Fever, Biology, Ecology, Evolution, Behavior and Systematics, Immunology and Microbiology, Base Sequence, Ecology, molecular typing, R, Dispatch, Life Sciences, Typing, Immunohistochemistry, Bluetongue Virus and Culicoides-Borne Diseases in Europe, RMSF, Virus, PCR, Infectious Diseases, Tick-Borne Diseases and Pathogens Transmission, Child, Preschool, FOS: Biological sciences, immunohistochemistry, Medicine, Female, Parasitology, Rocky Mountain spotted fever, Viral Hemorrhagic Fevers and Zoonotic Infections, Spotted fever
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