Japanese B Encephalitis Virus in Tissue Culture.

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1957 English Publisher:Frontiers Media SAJournal:Experimental Biology and Medicine, volume 94, pages 556-560 (issn: 1535-3702, eissn: 1535-3699,

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Authors: R W, MCCOLLUM; J F, FOLEY;

doi: 10.3181/00379727-94-23011

pmid: 13408325

Japanese B Encephalitis Virus in Tissue Culture.

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Abstract

SummaryTwo strains of Japanese B encephalitis virus have been serially propagated in tissue cultures of chick embryo fibroblasts (both plasma-clot explants and trypsinized cells), monkey kidney epithelium. HeLa cells, and Detroit-6 cells. Cytopathogenicity, which was consistent and reproducible, was observed only with the Detroit-6 cells. Maximal virus growth and release was observed 2 days before CPE became pronounced. This effect was readily neutralized by JBE immune serum. A similar CPE has been observed in Detroit-6 cells infected with the Egypt 101 strain of West Nile virus.

Related Organizations

Yale University
United States

Keywords

Encephalitis Virus, Japanese, Viruses, Encephalitis, Japanese

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