In experiments in our laboratory, where perfusinos were made on small animals, ligatures were made around the aorta in 4 places. Since a rather large number of operations were to be performed, a faster method was sought to make these ties. The instrument shown in Fig. 1 was made. In use the needle acts as a probe which once pushed completely under the vessel to be tied supplies the tying thread. The needle is withdrawn and the threat cut with the cutting blade attached to attaching the blade, the needle hub is wrapped with threat, then the blade set in place and wrapped with 21 gauge copper wire. The thread supplies enough springiness so that when the blade becomes dull it can be pushed out and another slid into place on the needle.The thread is wound into a coil as shown in Fig. 2. A motor drives the tapered glass rod for coiling the thread which is held lightly at the small end with the fingers. Six yards of triple zero surgical silk is wound in a coil 10 cm long while moving the string back and forth. ...