Biological Precursors of Biotin and/or Biotin L-Sulfoxide

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1955 English Publisher:Frontiers Media SAJournal:Experimental Biology and Medicine, volume 89, pages 234-236 (issn: 1535-3702, eissn: 1535-3699,

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Authors: L D, WRIGHT; E L, CRESSON; C A, DRISCOLL;

doi: 10.3181/00379727-89-21768

pmid: 14395276

Biological Precursors of Biotin and/or Biotin L-Sulfoxide

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Abstract

SummaryPimelic and azelaic acids were found to be precursors of biotin L-sulfoxide in the growth of Aspergillus niger. Shorter chain dicarboxylic acids as well as suberic and se-bacic acids are inactive. A number of other miscellaneous compounds including oleic acid, Tween 80, and certain “traumatic acids, v with structural or functional relationships to biotin and/or pimelic or azelaic acid only in approximate carbon chain length are inactive. A number of other compounds including cystine and certain purine and pyrimidine derivatives do not augment the dicarboxylic acid effect.

Related Organizations

Merck & Co.
United States

Keywords

Sulfoxides, Biotin, Humans

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