Biosynthesis of Radioactive Allantoin.

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1950 English Publisher:Frontiers Media SAJournal:Experimental Biology and Medicine, volume 75, pages 794-796 (issn: 1535-3702, eissn: 1535-3699,

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Authors: J D, VALENTINE; S, GURIN; D W, WILSON;

doi: 10.3181/00379727-75-18345

pmid: 14808406

Biosynthesis of Radioactive Allantoin.

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Abstract

Summary1. A convenient method for the isolation of allantoin from the urine of rats has been developed. 2. The carbon of sodium bicarbonate is not incorporated in the urinary allantoin of rats. This result is in accord with the fact that bicarbonate is incorporated only into position 6 of purines. 3. The carboxyl carbon of acetate is not involved in the biosynthesis of allantoin in the rat. 4. The carboxyl carbon of glycine is incorporated into position 4 of allantoin and the methylene carbon into position 5.

Related Organizations

University of Pennsylvania
United States

Keywords

Radioactivity, Allantoin

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