Inhibition of Calcification in vitro by Surface Active Compounds.

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1950 English Publisher:Frontiers Media SAJournal:Experimental Biology and Medicine, volume 75, pages 142-145 (issn: 1535-3702, eissn: 1535-3699,

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Authors: S, NOBEL;

doi: 10.3181/00379727-75-18126

pmid: 14797762

Inhibition of Calcification in vitro by Surface Active Compounds.

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Abstract

SummaryCalcification in vitro of the hypertrophic epiphyseal cartilage was found to be inhibited by 4.8 × 10−4 M sodium desoxycholate, 1.9 × 10−3 M sodium cholate, 1.4 × 10−3 M Duponal C, and .08% Tween−20. By preliminary treatment of rachitic sections with higher concentrations of these surface active agents for a short time interval, it was possible to demonstrate inhibition only with the bile salts and Duponal C.

Related Organizations

Lenox Hill Hospital
United States

Keywords

Surface-Active Agents, Calcification, Physiologic, Calcinosis, In Vitro Techniques

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