Ovarian Dehydrogenase Activities: Suggested Adrenal Involvement in Luteolysis
Copyright policy )Ovarian Dehydrogenase Activities: Suggested Adrenal Involvement in Luteolysis
Immature rat ovarian dehydrogenase activity was studied during corpus luteum regression following withdrawal of prior pregnant mare serum gonadotrophin. Glucose-6-phosphate dehydrogenase activity declined to nontreatment levels whereas 6-phosphogluconate, malate, and isocitrate dehydrogenase dehydrogenases exhibited a partial return to normal. Adrenalectomy prior to PMS withdrawal enhanced the decline in MAD while sharply elevating G6PD and 20alpha-hydroxysteroid dehydrogenase. Corticosterone and progesterone prevented the G6PD changes induced by adrenalectomy and moderated the rise in 20alpha-OHSD. Adrenalectomy appears to enhance the process of luteolysis.
- Rutgers, The State University of New Jersey United States
Gonadotropins, Equine, Phosphogluconate Dehydrogenase, Luteolysis, Ovary, Hydroxysteroid Dehydrogenases, Adrenalectomy, Glucosephosphate Dehydrogenase, Isocitrate Dehydrogenase, Rats, Alcohol Oxidoreductases, Malate Dehydrogenase, Animals, Female, Corticosterone, Progesterone
Gonadotropins, Equine, Phosphogluconate Dehydrogenase, Luteolysis, Ovary, Hydroxysteroid Dehydrogenases, Adrenalectomy, Glucosephosphate Dehydrogenase, Isocitrate Dehydrogenase, Rats, Alcohol Oxidoreductases, Malate Dehydrogenase, Animals, Female, Corticosterone, Progesterone
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