Corticosterone in Lymphoma-Bearing Rats.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1963 English Publisher:Frontiers Media SAJournal:Experimental Biology and Medicine, volume 113, pages 317-319 (issn: 1535-3702, eissn: 1535-3699,

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Authors: L, PERIC-GOLIA; R S, JONES;

doi: 10.3181/00379727-113-28353

pmid: 13942405

Corticosterone in Lymphoma-Bearing Rats.

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Abstract

SummaryCorticosterone in plasma and urine was determined by spectrofluorometry in sulfuric acid and by direct spectrophotometry in ethanol. Plasma levels and urinary excretion of corticosterone were elevated in rats with subcutaneous lymphomas. The high plasma concentration of corticosterone in these rats may help to explain the reduction in splenic, thymic and lymphoid tissue of lymphoma-bearing rats and certain interactions of exogenous steroids, quantity of lymphoma tissue and tumor-necrotizing effect of K. pneumoniae polysaccharide.

Related Organizations

University of Utah
United States

Keywords

Lymphoma, Animals, Corticosterone, Rats

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