Replication of Virus Plaques

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1961 English Publisher:Frontiers Media SAJournal:Experimental Biology and Medicine, volume 107, pages 790-793 (issn: 1535-3702, eissn: 1535-3699,

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Authors: A, BROWN; J E, OFFICER;

doi: 10.3181/00379727-107-26756

pmid: 13873567

Replication of Virus Plaques

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Abstract

SummaryOne of the 2 suspended cell plaque technics described by Cooper(5) has been modified so that its sensitivity and precision for plaque assay of VEE and EEE virus are satisfactory for general purposes. In addition, the modified suspended cell technic permitted nearly quantitative replication of virus plaques. Feasibility of the method in simulated systems for screening of host range or antigenic type recombinants (or mutants) was demonstrated.The excellent technical assistance of Mr. Delbert Davisson in this work is gratefully acknowledged.

Related Organizations

United States Department of the Army
United States

Keywords

DNA Replication, Viruses, Plaque, Amyloid

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