Popularly known as “tick disease”, canine ehrlichiosis is an infectious and endemic disease in several regions of Brazil, including Minas Gerais’ Midwest. Currently, it has been showing a high prevalence where the climate is favorable for the growth of its transmitting agent, the tick Rhipicephalus sanguineus, which during blood repast inoculates the infectious forms of Erlichia spp. with its saliva, transmitting the disease. A maltese dog, approximately 6 years old, had no ticks and her symptoms were indicating a hemoparasitosis. At first, ehrlichiosis was discarded due to tick absence. However, clinical trial and blood tests did not allow us to discard this disease. Serological test confirmed the ehrlichiosis. Treatment was conduct with recommended therapy and the animal responded well to treatment.